Chlorhexidine digluconate CHG

Pharmacological Action:

Chlorhexidine digluconate is a cationic surfactant preservative with broad-spectrum antibacterial activity. Its mechanism of action is to change the permeability of bacterial cell membranes. Certain Staphylococcus, Streptococcus mutans, Streptococcus salivarius, Candida albicans, Escherichia coli, and anaerobic propionic bacteria are highly sensitive, Streptococcus haemophilus is moderately sensitive, and Proteus, Pseudomonas, Klebsiella, and gram-negative coccus (e.g., Veillonella) are less sensitive. Its antibacterial action against gram-positive and Gram-negative bacteria. This product is still effective in the presence of serum, blood, etc. The action mechanism of this product is to adsorb on the infiltration barrier of the bacterial cytoserous membrane, causing the cell contents to leak out and play an antibacterial role. Low concentration has bacteriostatic effect, high concentration has bactericidal effect.

Uses  

Antiseptic, has quite strong broad spectrum bacteriostatic, bactericidal action, to Gram positive bacteria and gram negative bacteria have inhibition ability. Widely used for skin disinfection, surgical disinfection, instrument disinfection irrigation wound, bladder irrigation burns, burns, can also be used for oral anti-inflammatory, healing sore and abdominal cavity and intestinal mucosa disinfection in surgery, also used for daily tableware, vegetables and fruits, drinking water disinfection. Chlorhexidine gluconate aqueous solution is often prepared clinically for various purposes of disinfection.

Usage Method

Chlorhexidine gluconate is often used as a formula with other disinfection agents. The specific formula, usage and dosage should be determined according to the experimental results of equipment and equipment. A 2% aqueous solution is recommended for use as a disinfectant alone.